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Anabolic steroid- and exercise-induced cardiac stress protein (HSP72) in the rat BJMBR
Lunz,W.; Oliveira,E.C.; Neves,M.T.D.; Fontes,E.P.B.; Dias,C.M.G.C.; Natali,A.J..
The present study investigated the effects of exercise and anabolic-androgenic steroids on cardiac HSP72 expression. Male Wistar rats were divided into experimental groups: nandrolone exercise (NE, N = 6), control exercise (CE, N = 6), nandrolone sedentary (NS, N = 6), and control sedentary (CS, N = 6). Animals in the NE and NS groups received a weekly intramuscular injection (6.5 mg/kg of body weight) of nandrolone decanoate, while those in the CS and CE groups received mineral oil as vehicle. Animals in the NE and CE groups were submitted to a progressive running program on a treadmill, for 8 weeks. Fragments of the left ventricle were collected at sacrifice and the relative immunoblot contents of HSP72 were determined. Heart weight to body weight ratio...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Physical activity; Nandrolone; Myocardium; Heat shock protein.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000700006
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